PRP / PRF Face

A PRP facial is a regenerative skin treatment that uses nothing but your own blood. We take a small blood sample on the day of your treatment, concentrate the platelets and the growth factors they carry, and return them to the skin where it needs repair. In other words, you use your own naturally extracted growth factors to renew your own skin. You can choose PRP or PRF.

PRP is one of the most popular treatments in our aesthetic department, and we are proud to be among the early pioneers of this protocol in Bangkok and Thailand. It took time, research and real clinical experience to develop a protocol that delivers what we believe is the most natural and safe PRP for our patients. The treatment has also become well known as a celebrity favorite, with names such as Kim Kardashian, Bar Refaeli and Ferne McCann among its fans.

The published evidence supports a cautiously optimistic view: studies show PRP can improve skin texture, fine lines and collagen density. Results vary from person to person, and PRP is a genuinely promising, evidence-backed regenerative treatment, not a magic cure.

What it is and how it works

Blood contains red and white blood cells and platelets. Platelets are tiny blood cells that play a crucial part in helping the body stop bleeding, as well as in repairing damaged blood vessels and cells. They help the blood clot and contain hundreds of proteins called growth factors, which are beneficial for healing injuries. You can think of platelets as little powerhouses that release growth proteins when they come into contact with the body's tissue.

Platelet-rich plasma (PRP) is a preparation of platelets in concentrated blood plasma. By concentrating your platelets, PRP concentrates their growth factors too: the concentration of platelets in PRP can be 5 to 10 times greater, or "richer", than the usual distribution in the blood. These growth factors improve cellular activity and stimulate skin healing, collagen production and other important proteins that support the skin.

When PRP is returned to the skin, it triggers collagen production by stimulating the body's natural wound-healing response. Cell turnover is encouraged, which leads to more collagen and elastin. Collagen is the latticework of the face, so the skin becomes smoother, tighter and fuller, with better texture and tone. Because PRP works with your own biology, it essentially mimics your body's own healing process, using nothing foreign, and your body will not reject it. There is no risk of an allergic reaction.

PRP originated in orthopedic medicine and reconstructive surgery, where it has been used for decades to improve recovery naturally. Orthopedic doctors have injected PRP to heal injured joints, typically ankles, knees and elbows, for many years, and wound-care physicians have used it for wound and soft-tissue healing. Dermatologists more recently started using PRP to stimulate collagen production. Because it uses your own biology, PRP can be used in many places: the facial skin, the hair and even the joints.

Ways to deliver PRP to the face

We offer several PRP techniques, and you can choose the one that suits you best:

PRP with microneedling. The plasma is spread on the face, followed by microneedling across the cheeks and forehead to help the skin absorb the growth factors.
Intradermal or subcutaneous PRP injection (plasma filler). PRP is injected into the skin of the face or neck, into the areas of concern.

PRP can also be applied topically after laser treatment.

Microneedling, also called collagen induction therapy, is exactly what it sounds like: a procedure that creates a series of tiny, superficial punctures in the skin using short, sterile needles. The punctures allow ideal absorption of skincare, or of PRP, and rebuild collagen and elastin, producing a tightening effect. Both PRP and microneedling stimulate collagen growth, and they are complementary when done together. We have seen enhanced benefits from adding microneedling to PRP facial rejuvenation, and we believe this combination is one of the best anti-aging procedures for harnessing your body's natural healing power. It results in a more even skin tone and smoother skin.

What it is for

PRP / PRF Face is for glow, texture and skin renewal. PRP can:

Increase collagen production
Reduce fine lines and wrinkles
Improve the appearance of scars and stretch marks
Rejuvenate the under-eye area
Tighten stubborn open pores and minimize pore size
Firm and tighten the skin
Improve moisture retention
Enhance skin tone and texture
Decrease hyperpigmentation and pigmented spots
Plump and volumize areas such as the cheeks, where someone might otherwise have fillers, and volumize facial contours
Help reverse sun damage (photoaging)

When microneedling is added, further benefits include softening of stretch marks, increased skin firmness and tightness, reduction of hyperpigmentation and pore size, minimization of broken capillaries and spider veins, and improved skin texture and appearance of scars.

Reversing sun damage

Repeated exposure to ultraviolet (UV) radiation, mainly from the sun but also from UV lamps, causes photoaging: a premature aging of the skin. Its signs can show in many ways, including melasma, freckles, actinic keratoses, wrinkles, laxity and texture changes. Photoaging is the part of "aging" that is least about the calendar and most about the sun, and almost every adult's skin shares some of it.

Wearing sunscreen every day helps prevent skin cancer, and it also prevents signs of photoaging. If you already show some of its effects, you will want a treatment designed to reverse sun damage, and this is where PRP has become one of the most compelling anti-aging tools for the skin. The research increasingly shows that PRP does not just cover sun damage: it helps the skin repair it. PRP bathes troubled cells in a concentrated mixture of your own platelets, which are ordinarily responsible for wound healing and clotting and kick-start the body's natural processes to repair damaged tissue. In studies, PRP:

Increased the number of fibroblasts
Increased blood vessels in the skin
Increased collagen density in the skin
Produced significant improvements on wrinkle, elastosis and photoaging scoring scales

Who it is for

PRP / PRF Face suits people who want a natural result with a natural product, their own platelets, and who would like to improve lines and wrinkles without surgery. It is useful for those with scars, wrinkles or sun damage, and the procedure is safe for almost everyone.

Who should not have it

People with clotting conditions that require blood thinners.
People with other blood-related health issues.

When the skin is quite loose or has extreme sun damage, non-invasive treatments may not produce a dramatic improvement, and surgery is likely to be the better option. Your doctor will discuss this with you at your consultation.

The treatment

The treatment takes 45 to 60 minutes. PRP facials are medical, rather than cosmetic, procedures.

We recognize that every patient has individual preferences, and we tailor the treatment to suit you. Tell us which area you would like to address and which method you prefer, PRP or PRF, and whether you would like microneedling, injection or both. Drawing on our extensive experience with this treatment, we follow specialized guidelines to ensure optimal results.

Numbing. Your doctor applies a topical numbing cream to the treatment areas and leaves it to take full effect, ideally for about 30 to 40 minutes.
Blood draw. While the numbing takes effect, a small amount of your blood is drawn from your arm. This is quick and nearly painless, as we collect only one 30 ml vial.
Preparation. Your blood is placed in an FDA-cleared device and spun in a centrifuge for 9 minutes. This separates it into PRP (platelet-rich plasma, gold in color), PPP (platelet-poor plasma, clear) and red blood cells (red). The PRP and PPP are then transferred into separate syringes.
Injection. The PRP is injected into your areas of concern.
Microneedling. The PPP is brushed onto the skin to serve as the lubricant for microneedling. A typical microneedling procedure uses a hyaluronic acid serum or another serum for this; with PRP, your own plasma does the job.

Immediately after treatment, you may look as though you have a moderate to severe sunburn, and your skin may feel warmer and tighter than usual. While the immediate results may not look ideal, the controlled inflammation corrects the areas of concern and triggers cellular rejuvenation. Your glowing skin will appear over the following weeks and last for months.

How many sessions?

The number of sessions is always set by your doctor after an in-person assessment. Each treatment is completed in a single visit. For the best results, a series of treatments 4 to 6 weeks apart is usually recommended, and additional maintenance procedures may be needed as time passes. With microneedling, patients typically see the best results in skin tone after the second or third treatment, with continued improvement in the following months. Several treatments can be combined on the same day, as your doctor advises.

Before and aftercare

Aftercare is a crucial factor in the success of the procedure. After the treatment, the work is done by your body, which naturally produces new cells and collagen. To help it perform at its best:

Before bedtime, wash your face with cold water and no soap, then gently massage the face with tepid water to remove all serum and dried blood.
Do not apply sunscreen or makeup for 12 hours after treatment. Regular makeup can be applied normally from the day after treatment.
Apply a generous amount of moisturizer for sensitive skin. Your own skin cells, including your fibroblasts, work with the treatment, and they perform best on moist rather than dry skin.
For the first 2 weeks, use only products for sensitive skin to prevent irritation.
For at least 3 days, do not use alpha hydroxy acids (AHAs), retinol, vitamin A, vitamin C or anything else considered active skincare.
Avoid alcohol-based toners and whitening products for 10 to 14 days.
Avoid direct sunlight for 24 to 48 hours, and avoid excessive sun exposure for 10 days.
Use sunscreen daily, SPF 25 or higher.
Do not exercise for 24 hours after treatment.
Do not go swimming for at least 5 days after treatment.
Pay attention to your nutrition: avoid high-sugar foods, and make sure you get enough protein and vitamin C, as they are essential building blocks for new collagen.
Do not smoke, and limit exposure to passive smoking for as long as possible.

Quality and safety

Stand-alone PRP / PRF Face uses only your own blood, drawn on the day of your treatment. The product returned to your skin is 100% your own.
Your blood is processed in an FDA-cleared device.
Side effects of PRP treatment in studies were minimal to mild, with excellent tolerability.
The patient's own growth factors mean there is no risk of rejection or allergic reaction.

We believe healing is not only a tablet or a needle; it is the whole experience. The clinic has been designed as a calm, natural setting where patients can feel positive and relaxed: no rushing, no pushing, no pressure, none of the worry you might feel in a busy hospital. When your nervous system is calm and you feel safe, your body is in a better place to repair, and that fits naturally with how regenerative treatments work.

We choose the doctors carefully. A Western study and training background is one of our criteria, because it keeps communication smooth and standards high, but professionalism and a true service mind matter just as much. When you come for a healthcare service, it usually is not your field, and sometimes you do not even know what to ask, so the team aims to give you the information you need before you have to ask for it. What is routine for us is not routine for you, and many patients feel nervous on their first visit, so we do our best to take good care of you. We do not run paid marketing; we rely on patient education and word of mouth.

The science

How PRP rebuilds the skin

A meta-analysis pooling several randomized controlled trials, with hundreds of patients, found that PRP significantly improved both patient satisfaction and objective measures of skin improvement compared with control treatments. [2]
Histology studies, in which skin samples are examined under the microscope, show that PRP triggers a fibroblast response that increases collagen, thickens the dermis and improves skin elasticity and density. [3][7]
PRP has been reported to boost the skin's own hyaluronic acid synthesis and collagen production, leading to smoother, tighter skin, with improvements in pore size, texture, fine lines and pigmented spots after just one to three sessions. [1][7]
Ultrasound studies measuring skin density and thickness confirm that PRP can meaningfully build up the skin's structure, with patient age influencing how strong the response is. [8]
PRP contains growth factors that improve cellular activity and boost collagen production (study).
A September 2017 study in the Aesthetic Surgery Journal found that after an injection of PRP, doctors observed an increase in the thickness of the reticular dermis, the lower of the two layers of the dermis. This thickening was caused by the deposition of elastic fibers, which give skin its elasticity, and collagen, with a fibrotic (regenerative) aspect. The researchers concluded: "PRP injection could lead to trophic alteration of the skin and the precocious aging process."

PRP and sun damage

In laboratory and animal studies, skin exposed to UV develops the familiar signs of damage: redness, wrinkling and breakdown of collagen. Treatment with PRP has been shown to improve this aged, damaged skin while reducing harmful oxidative stress and protecting against collagen degradation. [4] At the molecular level, PRP appears to block the UV-driven enzymes, such as MMP-1, that tear down collagen and elastin, while helping restore the elastic fibers that give young skin its bounce. [5] In studies on UV-damaged skin cells, PRP given before and after exposure strengthened the cells' own antioxidant defenses, reduced DNA damage and encouraged the damaged cells to recover and multiply. [6] In short, PRP works with the same biology your skin uses to heal a wound and points it at the slow, accumulated injury of sun exposure.

PRP with microneedling or hyaluronic acid

PRP works well with other treatments. Combining PRP with hyaluronic acid, or with microneedling, has shown greater improvement in skin elasticity and appearance than either approach alone. [7] This is one reason we pair treatments thoughtfully rather than relying on a single tool. The Journal of Plastic, Reconstructive and Aesthetic Surgery has described "microneedling as a safe and effective therapeutic option for the treatment of scars and wrinkles."

An honest note

PRP science is still maturing. Preparation methods and study designs vary, so researchers rightly call for more standardized trials. We share results with you honestly: PRP is a genuinely promising, evidence-backed regenerative treatment, not a miracle, and outcomes differ from person to person.

References

Hesseler MJ, Shyam N. "Platelet-rich plasma and its utility in the treatment of acne scars and skin rejuvenation" / systematic appraisals of PRP in facial rejuvenation. Clinical, Cosmetic and Investigational Dermatology. Link
"Efficacy of platelet-rich plasma in facial rejuvenation: A systematic review." ScienceDirect (2025). Link
"Histologic Evidence of New Collagen Formation Using Platelet Rich Plasma in Skin Rejuvenation: A Prospective Controlled Clinical Study." PubMed. Link
"Platelet-rich plasma alleviates skin photoaging by activating autophagy and inhibiting inflammasome formation." Naunyn-Schmiedeberg's Archives of Pharmacology (2025). Link
"Platelet-rich plasma regulating the repair of ultraviolet B–induced acute tissue inflammation." Bioengineered (2021). Link
"The Anti-photoaging Effects of Pre- and Post-treatment of Platelet-rich Plasma on UVB-damaged HaCaT Keratinocytes." PubMed. Link
"Use of platelet rich plasma for skin rejuvenation." Skin Research and Technology (2024). Link
"Effect of Patient Age on Platelet-Rich Plasma (PRP) and Fibrin Treatments for Skin Density and Thickness: A Single-Center Ultrasound Study." Life (2025). Link

Frequently asked questions

What is a PRP facial, and how does it work?

A PRP facial uses platelet-rich plasma drawn from your own blood. The concentrated platelets release growth factors that signal your skin to repair itself, boosting collagen, improving texture and supporting a fresher appearance over time. Because it uses your own biology, it is a natural, low-risk approach, though results build gradually and vary between people. [1][2]

How soon will I see results?

Many patients notice fresher, brighter skin within a few weeks to a month, with continued improvement as collagen rebuilds. A short series of sessions is often recommended. Individual results differ, and your doctor will set realistic expectations during your consultation. [2][3] One patient, who was a little nervous on her first visit, told us a month later that her skin already looked noticeably fresher and brighter.

What is the difference between PRP and a dermal filler?

PRP is extracted from your own blood and injected into the skin to rejuvenate it. It uses the growth factors found in your blood, so your body will not reject it, and it works by improving cellular activity and boosting collagen production.

Dermal fillers focus on "filling" the hollow parts of the face that have lost volume, adding volume to the cheeks and the sunken areas of the lower half of the face (study). They are not permanent. In rare cases, fillers can cause a blood-vessel blockage leading to skin death or blindness, or lumps under the skin.

How long do the results of plasma filler last?

The results of PRP treatments typically last longer than dermal fillers. Depending on the number of treatment sessions, PRP results last from 12 months up to 24 months, while dermal fillers last from 8 to 18 months before losing their effect.

How is PRP different from stem cell treatment?

Both are regenerative, and both use healing signals. PRP concentrates the growth factors from your own blood, while stem cell therapy uses regenerative cells. They are complementary tools, and the right choice depends on your goals and a proper assessment by your doctor.

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